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References   References 4516  
Type : Journal
Research teams : Cambridge - Amgen Inc, USA
Authors : Seckute J, Castellanos I, Bane S.
Title : Physicochemical stability of the bevacizumab biosimilar, ABP 215, after preparation and storage in intravenous bags.
Reference : GaBI Journal ; 9, 4:155-162 2020
Level of Evidence : 
Level of evidence A+
Physical stability : 
Particle counting Protein: Size Exclusion Chromatography 
Chemical stability : 
Protein: ionic chromatography
Capillary electrophoresis
Other methods : 
Protein: biological activity 
Comments : 
List of drugs
InjectionBevacizumab Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1,4 >>16,5 mg/ml 2-8°C Not specified
35 Day
Biosimilar
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1,4 >>16,5 mg/ml 30°C Light
2 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 1,4 >>16,5 mg/ml 2-8°C Not specified
35 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 1,4 >>16,5 mg/ml 30°C Light
2 Day
Biosimilar
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