Last update :
19/11/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
valistab
valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 4505  
Type : Journal
Web link : https://doi.org/10.1016/j.ejca.2020.04.042
Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Le Guyader G, Vieillard V, Mouraud S, Do B, Marabelle A, Paul M.
Title : Stability of nivolumab in its original vials after opening and handing in normal saline bag for intravenous infusion.
Reference : Eur J Cancer ; 135: 192-202. 2020
Level of Evidence : 
Level of evidence A+
Physical stability : 
Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ultraviolet spectrometry and second derivative
Protein: ionic chromatography
Other methods : 
PH measurement Protein: biological activity 
Comments : 
List of drugs
injectionNivolumab Anticancer drug
Stability in solutions Glass None 10 mg/ml 40°C Not specified
7 Day
Stability in solutions partially used vials None 10 mg/ml 2-8°C Not specified
28 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 2 mg/ml 2-8°C Not specified
28 Day
  Mentions Légales