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References   References 4479  
Type : Journal
Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Closset M, Goderniaux N, Colsoul M-L, Soumoy L, Bihin B, Jamart J, Odou P, Hecq J-D, galanti L.
Title : Long term stability of an admixture of alizapride and ondansetron in 0.9% sodium chloride solution polyolefin bags stored at 5 +/- 3°C.
Reference : J Oncol Pharm Practice ;27,6:1328-1332 2020
Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
List of drugs
injectionAlizapride hydrochloride Antiemetic
Compatible 0.92 mg/ml + injectionOndansetron hydrochloride 0.07 mg/ml + Sodium chloride 0,9%
injectionOndansetron hydrochloride Antiemetic
Compatible 0.07 mg/ml + injectionAlizapride hydrochloride 0.92 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Polyolefine Sodium chloride 0,9% 2-8°C Not specified
injection Alizapride hydrochloride 0,926 mg/ml
injection Ondansetron hydrochloride 0,074 mg/ml
56 Day
  Mentions Légales