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References   References 4473  
Type : Journal
Web link : 10.1111/ner.13218
Research teams : Angers - Institut de cancérologie de l’ouest - Paul Papin, Pharmacy Department
Authors : Robert J, Sorrieul J, Andrieu A, Mounsef F, Dupoiron D, Devys C.
Title : Study of Physicochemical Stability of Ziconotide in Medication Cassette Reservoir.
Reference : Neuromodulation 2020
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products detected but not quantified
List of drugs
injectionZiconotide acetate Analgesic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0.4 & 0.6 µg/ml 23-27°C Protect from light
48 Hour
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