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References   References 439  
Type : Journal
Research teams : San Antonio - Murphy Memorial Veterans Hospital
Authors : Kintzel PE, Kennedy PE.
Title : Stability of amphotericin B in 5% dextrose injection at concentrations used for administration through a central venous line.
Reference : Am J Hosp Pharm ; 48: 283-285. 1991
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Changes in pH not commented or difficult to interpret
Degradation products not observed in real conditions
List of drugs
injectionAmphotericin B Antifungal
Stability in solutions Polyolefine Glucose 5% 0,92 >> 1,4 mg/ml 25°C Not specified
36 Hour
Stability in solutions Polyolefine Glucose 5% 0,92 >> 1,4 mg/ml 6°C Protect from light
36 Hour
  Mentions Légales