Last update :
19/11/2024
References   References 436  
Type : Journal

Research teams : Boston - New England Deaconess Hospital
Authors : Mitrano FP, Outman WR, Baptista RJ, Palombo JD.
Title : Chemical and visual stability of amphotericin B in 5% dextrose injection stored at 4°C for 35 days.
Reference : Am J Hosp Pharm ; 48: 2635-2637. 1991

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionAmphotericin B Antifungal
Stability in solutions Polyvinyl chloride Glucose 5% 0,1 & 0,25 mg/ml 4°C Protect from light
35 Day

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