Last update :
16/06/2024
References   References 4334  
Type : Journal
Web link : https://doi.org/10.1177/1078155219868516

Research teams : West Point - Merck and Co
Authors : Sundaramurthi P, Sean Chadwick S, Narasimhan C.
Title : Physicochemical stability of pembrolizumab admixture solution in normal saline intravenous infusion bag.
Reference : J Oncol Pharm Practice ; 26, 3: 641-646. 2020

Level of Evidence : 
Level of evidence A+
Physical stability : 
Size Exclusion Chromatography Visual examination Particle counting 
Chemical stability : 
Protein: ionic chromatography
Capillary electrophoresis
Other methods : 
PH measurement Protein: biological activity 
Comments : 

List of drugs
InjectionPembrolizumab Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 1 mg/ml 17-23°C Light
7 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 1 mg/ml 2-8°C Light
7 Day

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