Last update :
18/07/2024
References   References 431  
Type : Journal

Research teams : Stockton - University of the Pacific, Department of Pharmaceutics and Medical Chemistry
Authors : McRae MP, King JC.
Title : Compatibility of antineoplastic, antibiotic and corticosteroid drugs in intravenous admixtures.
Reference : Am J Hosp Pharm ; 33: 1010-1013. 1975

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionCefalotin sodium Antibiotic
Compatible 1 mg/ml + injectionCytarabine 0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionFluorouracil 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMethotrexate sodium 0.4 mg/ml + Glucose 5%
injectionCytarabine Anticancer drug
Compatible 0.8 mg/ml + injectionCefalotin sodium 1 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectionFluorouracil 0.25 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectionMethotrexate sodium 0.2 mg/ml + Glucose 5%
Compatible 0.016 mg/ml + injectionVincristine sulfate 0.004 mg/ml + Glucose 5%
injectionFluorouracil Anticancer drug
Compatible 0.5 mg/ml + injectionCefalotin sodium 1 mg/ml + Glucose 5%
Incompatible 0.25 mg/ml + injectionCytarabine 0.4 mg/ml + Glucose 5%
Incompatible 0.25 mg/ml + injectionMethotrexate sodium 0.2 mg/ml + Glucose 5%
Compatible 0.010 mg/ml + injectionVincristine sulfate 0.004 mg/ml + Glucose 5%
injectionMethotrexate sodium Anticancer drug
Compatible 0.4 mg/ml + injectionCefalotin sodium 1 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + injectionCytarabine 0.4 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + injectionFluorouracil 0.25 mg/ml + Glucose 5%
Compatible 0.008 mg/ml + injectionVincristine sulfate 0.004 mg/ml + Glucose 5%
injectionVincristine sulfate Anticancer drug
Compatible 0.004 mg/ml + injectionCytarabine 0.016 mg/ml + Glucose 5%
Compatible 0.004 mg/ml + injectionFluorouracil 0.010 mg/ml + Glucose 5%
Compatible 0.004 mg/ml + injectionMethotrexate sodium 0.008 mg/ml + Glucose 5%

  Mentions Légales