Last update :
28/04/2024
References   References 431  
Type : Journal

Research teams : Stockton - University of the Pacific, Department of Pharmaceutics and Medical Chemistry
Authors : McRae MP, King JC.
Title : Compatibility of antineoplastic, antibiotic and corticosteroid drugs in intravenous admixtures.
Reference : Am J Hosp Pharm ; 33: 1010-1013. 1975

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionCefalotin sodium Antibiotic
Compatible 1 mg/ml + InjectionCytarabine 0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionFluorouracil 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMethotrexate sodium 0.4 mg/ml + Glucose 5%
InjectionCytarabine Anticancer drug
Compatible 0.8 mg/ml + InjectionCefalotin sodium 1 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + InjectionFluorouracil 0.25 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + InjectionMethotrexate sodium 0.2 mg/ml + Glucose 5%
Compatible 0.016 mg/ml + InjectionVincristine sulfate 0.004 mg/ml + Glucose 5%
InjectionFluorouracil Anticancer drug
Compatible 0.5 mg/ml + InjectionCefalotin sodium 1 mg/ml + Glucose 5%
Incompatible 0.25 mg/ml + InjectionCytarabine 0.4 mg/ml + Glucose 5%
Incompatible 0.25 mg/ml + InjectionMethotrexate sodium 0.2 mg/ml + Glucose 5%
Compatible 0.010 mg/ml + InjectionVincristine sulfate 0.004 mg/ml + Glucose 5%
InjectionMethotrexate sodium Anticancer drug
Compatible 0.4 mg/ml + InjectionCefalotin sodium 1 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + InjectionCytarabine 0.4 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + InjectionFluorouracil 0.25 mg/ml + Glucose 5%
Compatible 0.008 mg/ml + InjectionVincristine sulfate 0.004 mg/ml + Glucose 5%
InjectionVincristine sulfate Anticancer drug
Compatible 0.004 mg/ml + InjectionCytarabine 0.016 mg/ml + Glucose 5%
Compatible 0.004 mg/ml + InjectionFluorouracil 0.010 mg/ml + Glucose 5%
Compatible 0.004 mg/ml + InjectionMethotrexate sodium 0.008 mg/ml + Glucose 5%

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