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References   References 4304  
Type : Journal
Web link : 10.1007/s40268-014-0037-9
Research teams : Villejuif - Institut Gustave Roussy, Department of Pharmacy
Authors : Klasen K, Kessari R, Mercier L, Valade C, Grill J, Desmaris R, Paci A.
Title : Stability of Etoposide Solutions in Disposable Infusion Devices for Day Hospital Cancer Practices.
Reference : Drugs R D ; 14:13?23. 2014
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionEtoposide Anticancer drug
Stability in solutions Polyisoprene elastomer NaCl 0,9% or Glucose 5% 0,4 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyisoprene elastomer NaCl 0,9% or Glucose 5% 0,4 mg/ml 33°C Protect from light
24 Hour
Stability in solutions Polyisoprene elastomer NaCl 0,9% or Glucose 5% 0,6 mg/ml 25°C Protect from light
8 Hour
Stability in solutions Polyisoprene elastomer NaCl 0,9% or Glucose 5% 0,6 mg/ml 33°C Protect from light
6 Hour
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,1 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,1 mg/ml 33°C Protect from light
24 Hour
Stability in solutions Polyisoprene elastomer Glucose 5% 0,1 mg/ml 25°C Protect from light
12 Hour
Stability in solutions Polyisoprene elastomer Glucose 5% 0,1 mg/ml 33°C Protect from light
12 Hour
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