Last update :
18/04/2024
References   References 430  
Type : Journal

Research teams : Houston - University of Houston, College of Pharmacy
Authors : Das Gupta V, Stewart KR, Nohria S.
Title : Stability of vancomycin hydrochloride in 5% dextrose and 0.9% sodium chloride injections.
Reference : Am J Hosp Pharm ; 43: 1729-1731. 1986

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Glass NaCl 0,9% or Glucose 5% 5 mg/ml -10°C Protect from light
63 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 5 mg/ml 24°C Not specified
17 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 5 mg/ml 5°C Protect from light
63 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 24°C Not specified
17 Day

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