Last update :
19/11/2024
References   References 4282  
Type : Journal
Web link : 10.1007/s40268-017-0183-y

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Myers A-L, Zhang Y-P, Kawedia J-D, Zhou X,. Sobocinski S-M, Metcalfe M-J, Kramer M-A, Dinney C.P.N, Kamat A-M.
Title : Solubilization and Stability of Mitomycin C Solutions Prepared for Intravesical Administration.
Reference : Drugs R D 2017

Level of Evidence : 
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionMitomycin Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 37°C Not specified
5 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 37°C Not specified
5 Hour

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