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References   References 4268  
Type : Journal
Web link : https://doi.org/10.1515/pthp-2019-0006
Icone.pdf
208Ko
Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : D'Huart E, Vigneron J, Blaise F, Charmillon A, Demoré B.
Title : Physicochemical Stability of Cefotaxime Sodium in Polypropylene Syringes at High Concentrations for Intensive Care Units.
Reference : Pharmaceutical Technology in Hospital Pharmacy 2019
Level of Evidence : 
Level of evidence B+
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
Measurement of osmolality 
Comments : 
List of drugs
injectionCefotaxime sodium Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 125 mg/ml 20-25°C Light
6 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 83,3 mg/ml 20-25°C Light
6 Hour
Stability in solutions Polypropylen Syringe Glucose 5% 125 mg/ml 20-25°C Light
6 Hour
Stability in solutions Polypropylen Syringe Glucose 5% 83,3 mg/ml 20-25°C Light
6 Hour
Compatible + Sodium chloride 0,9%
Compatible + Glucose 5%
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