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References   References 4245  
Type : Poster
Icone.pdf
1337Ko
Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Iazetta J, Law S, Adhikari NKJ, Lamontagne F, Kanji S, Walker SE.
Title : Physical Compatibility and Stability of Ascorbic acid Injection in Polyvinyl Chloride Minibags at 4ºC and Room Temperature (25ºC).
Reference : 2019
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No visual inspection
List of drugs
injectionAscorbic acid Vitamin
Factors which affect stability Temperature 25°C Induces Reduced stability
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 36,6 >> 91,4 mg/ml 25°C Protect from light
10 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 36,6 >> 91,4 mg/ml 4°C Protect from light
14 Day
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