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References   References 4178  
Type : Journal
Web link : https://ejhp.bmj.com/content/25/6/337
Research teams : Leiden - University Hospital Leiden, Department of clinical pharmacy and toxicology
Authors : Post T.E, Kamerling I, van Rossen R, Burggraaf J, Stevens J, Dijkmans A, Heijerman H, Touw D, van Velzen A, Wilms E.
Title : Colistin methanesulfonate infusion solutions are stable over time and suitable for home administration.
Reference : EJHP ; 25, e2 2017
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionColistin mesilate sodium Antibiotic
Stability in solutions Polyolefine Sodium chloride 0,9% 1,6 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 1,6 mg/ml 20-24°C With or without light
1 Day
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,8 & 2,4 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,8 & 2,4 mg/ml 20-24°C With or without light
1 Day
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