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References   References 4148  
Type : Journal
Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Huvelle S, Godet M, Galanti L, Closset M, Bihin B, Jamart J, Hecq J.D.
Title : Long-Term Stability Comparison between an Original and a Generic Version of Piperacillin/Tazobactam in Dextrose 5% Infusion Polyolefin Bags at 5+/-3°C after Microwave Freeze-Thaw Treatment.
Reference : Pharmaceutical Technology in Hospital Pharmacy 2018
Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
List of drugs
injectionPiperacillin sodium / tazobactam Antibiotic
Stability in solutions Polyolefine Glucose 5% 33,3 / 4,1 mg/ml -20°C Protect from light
90 Day
Stability in solutions Polyolefine Glucose 5% 33,3 / 4,1 mg/ml 2-8°C Not specified
58 Day
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