Last update :
03/05/2024
References   References 4126  
Type : Journal

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : D'Huart E, Vigneron J, Ranchon F, Vantard N, Rioufol C, Demor2 B
Title : Physico-Chemical Stability of Sodium Thiosulfate Infusion Solutions in Polyolefin Bags at Room Temperature over a Period of 24 Hours.
Reference : Pharmaceutical Technology in Hospital Pharmacy ;3,3:135-142 2018

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionSodium thiosulfate Antidote
Stability in solutions Polyolefine Sodium chloride 0,9% 16 mg/ml 25°C Light
24 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 72 mg/ml 25°C Light
24 Hour

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