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References   References 4125  
Type : Journal
Web link : 10.1136/ejhpharm-2018-001571
Icone.pdf
389Ko
Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : D'Huart E, Vigneron J, Lider P, Demoré B.
Title : Physicochemical stability of etoposide diluted at range concentrations between 0.38 and 1.75 mg/mL in polyolefin bags.
Reference : EJHP ; 27, 1: 43-48. 2020
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
InjectionEtoposide Anticancer drug
Stability in solutions Polyolefine Glucose 5% 0,38 mg/ml 25°C Protect from light
61 Day
Stability in solutions Polyolefine Glucose 5% 0,74 mg/ml 25°C Protect from light
61 Day
Stability in solutions Polyolefine Glucose 5% 1,26 mg/ml 25°C Protect from light
61 Day
Stability in solutions Polyolefine Glucose 5% 1,75 mg/ml 25°C Protect from light
28 Day
  Mentions Légales