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19/11/2024
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References 4097
Type :
Journal
Research teams :
Sevilla - University Hospital “Virgen del Rocío, Department of Pharmacy
Authors :
Casas M, Alvarez J, Lucero M.
Title :
Physicochemical stability of captopril and enalapril extemporaneous formulations for pediatric patients.
Reference :
Pharm Dev Technol 2013
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
List of drugs
Captopril
30 mg
® = ?
Sodium edetate
3 mg
Purified water
>> 30 mL
2-8°C
50
30 mg
® = ?
Sodium edetate
3 mg
Purified water
>> 30 mL
23-27°C
30
30 mg
® = ?
Sodium edetate
3 mg
Purified water
>> 30 mL
38-42°C
30
Enalapril maleate
30 mg
® = ?
Citric acid
177 mg
hydrochloric acid
0,1M 12,3 mL
NaOH
0,1M 1,7 mL
Purified water
8,5 mL
Simple syrup
>> 30 mL
2-8°C
50
30 mg
® = ?
Citric acid
177 mg
hydrochloric acid
0,1M 12,3 mL
NaOH
0,1M 1,7 mL
Purified water
8,5 mL
Simple syrup
>> 30 mL
23-27°C
50
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