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References   References 409  
Type : Journal
Research teams : Bethesda - National Institutes of Health Clinical Center
Authors : Cheung YW, Cradock JC, Vishnuvajjala BR, Flora KP.
Title : Stability of cisplatin, iproplatin, carboplatin, and tetraplatin in commonly used intravenous solutions.
Reference : Am J Hosp Pharm ; 44: 124-130. 1987
Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No comments for the degradation products
No visual inspection
List of drugs
injectionCarboplatin Anticancer drug
Factors which affect stability Solvent Sodium chloride 0,9% Induces Degradation
Incompatible + Sodium chloride 0,9%
injectionCisplatin Anticancer drug
Factors which affect stability [Cl-] < 0,3% Induces Degradation
  Mentions Légales