Last update :
24/05/2022
References   References 4029  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=4375

Research teams : Cleveland - Cleveland Clinic Fundation
Authors : Marquis K, Hohlfelder B, Szumita Paul.
Title : Stability of Dexmedetomidine in 0.9% Sodium Chloride in Two Types of Intravenous Infusion Bags.
Reference : Int J Pharm Compound ; 21, 5: 436-439 2017

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionDexmedetomidine Sympathomimetic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 4 µg/ml 20-25°C Not specified
14 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 4 µg/ml 3-4°C Not specified
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 4 µg/ml 20-25°C Not specified
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 4 µg/ml 3-4°C Not specified
14 Day

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