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References   References 4020  
Type : Journal
Web link : https://doi.org/10.1310/hpj4510-779
Research teams : Madison - University of Wisconsin-Madison, School of Pharmacy
Authors : T. Schulz L, J. Elder E, Jones K, Vijayan A, D. Johnson B, E. Medow J, Vermeulen L.
Title : Stability of Sodium Nitroprusside and Sodium Thiosulfate 1:10 Intravenous Admixture.
Reference : Hosp Pharm ;45,10:779?784 2010
Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionNitroprusside sodium Vasodilator
Compatible 0.2 mg/ml + injectionSodium thiosulfate 2 mg/ml + NaCl 0,9% or Glucose 5%
injectionSodium thiosulfate Antidote
Compatible 2 mg/ml + injectionNitroprusside sodium 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Stability of mixtures
Not specified Sodium chloride 0,9% 25°C Protect from light
injection Nitroprusside sodium 0,18 mg/ml
injection Sodium thiosulfate 1,8 mg/ml
48 Hour
Not specified Glucose 5% 25°C Protect from light
injection Nitroprusside sodium 0,18 mg/ml
injection Sodium thiosulfate 1,8 mg/ml
48 Hour
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