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References   References 4012  
Type : Journal
Web link : https://ejhp.bmj.com/content/25/e2/e102
Research teams : Hobart - University of Tasmania, School of Pharmacy
Authors : Khaleel I, Tabish R Zaidi S, Shastri M, Suji Eapen M, Chiau Ming L, Wanandy T, P Patel R.
Title : Investigations into the physical and chemical stability of concentrated co-trimoxazole intravenous infusions.
Reference : EJHP ; 25, e2 2018
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionCo-trimoxazole Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 3.33/0.66 mg/ml 20-22°C Light
4 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 4,21/0,84 mg/ml 20-22°C Light
4 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 5,71/1,14 mg/ml 20-22°C Light
2 Hour
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