Last update :
19/11/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
valistab
valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 40  
Type : Journal
Research teams : Lille - Faculté des Sciences Pharmaceutiques et Biologiques
Authors : Dine T, Lebegue S, Benaji B, Gressier B, Segard V, Goudaliez F, Luyckx M, Brunet C, Mallevais ML, Kablan J, Cazin M, Cazin JC.
Title : Stability and compatibility studies of four cytostatic agents (fluorouracil, dacarbazine, cyclophosphamide and ifosfamide) with PVC infusion bags.
Reference : Pharm Sci Communications ; 4: 97-101. 1994
Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Unencrypted results (eg graphic)
Degradation products not observed in real conditions
List of drugs
injectionCyclophosphamide Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 4°C Protect from light
30 Day
injectionDacarbazine Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1,6 mg/ml 4°C Protect from light
30 Day
injectionFluorouracil Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 4°C Protect from light
30 Day
injectionIfosfamide Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 30 mg/ml 4°C Protect from light
30 Day
  Mentions Légales