Type : |
Journal |
Web link : |
https://doi.org/10.2146/ajhp150818 |
|
Research teams : |
Odense - Odense University Hospital, Hospital Pharmacy |
Authors : |
Nissen K.B, Jorgensen L.B, Berg D.L, Andersen G. |
Title : |
Stability study of methotrexate in 0.9% sodium chloride injection and 5% dextrose injection with limit tests for impurities. |
Reference : |
Am J Health-Syst Pharm ; 74,9: e211-e223 2017 |
|
Level of Evidence : |
|
Physical stability : |
|
Chemical stability : |
|
Other methods : |
|
Comments : |
Degradation products identified |
|
List of drugs
Methotrexate sodium
|
|
|
|
|
0,2 mg/ml |
23-27°C |
|
28 |
|
|
|
|
|
|
20 mg/ml |
23-27°C |
|
28 |
|
|
|
|
|
|
0,2 mg/ml |
23-27°C |
|
3 |
|
|
|
|
|
|
20 mg/ml |
23-27°C |
|
28 |
|
|
|
|
|