Last update :
18/04/2024
References   References 3756  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=3893

Research teams : Rochester - Mayo Clinic, Department of pharmacy
Authors : McCluskey S.V, Sztajnkrycer M.D, Jenkins D.A, Zietlow S P, Berns K.S, Park Myung S.
Title : Stability of Tranexamic Acid in 0.9% Sodium Chloride, Stored in Type 1 Glass Vials and Ethylene/Propylene Copolymer Plastic Containers.
Reference : Int J Pharm Compound ; 18, 5: 423-437. 2014

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionTranexamic acid Anti-bleeding
Stability in solutions Glass Sodium chloride 0,9% 20 mg/ml 20-25°C Protect from light
180 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 15 mg/ml 2-8°C Protect from light
90 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 15 mg/ml 20-25°C Protect from light
90 Day

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