Last update :
19/11/2024
References   References 3754  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=3891

Research teams : Boston - Massachusetts Eye and Ear Infirmary, Harvard Medical School
Authors : Robert M.C, Spurr-Michaud S, Frenette M, Young D, Gipson Ilene K, Dohlman Claes H.
Title : Stability and In Vitro Toxicity of an Infliximab Eye Drop Formulation.
Reference : Int J Pharm Compound ;18, 5: 418-426. 2014

Level of Evidence : 
Physical stability : 
Visual examination Protein: Dynamic Light Scattering 
Chemical stability : 
Other methods : 
PH measurement Protein: biological activity 
Comments : 

List of drugs
Eye-dropsInfliximab Immunosuppressant
Stability in solutions Not specified Medicine bottle for injection 100 mg
Remicade ®
sodium carboxymethylcellulose 50 mg
boric acid
CaCl2
MgCl2
KCl
Water for injection >> 10 ml
-20°C Not specified
45 Day
Stability in solutions Not specified Medicine bottle for injection 100 mg
Remicade ®
sodium carboxymethylcellulose 50 mg
boric acid
CaCl2
MgCl2
KCl
Water for injection >> 10 ml
4°C Not specified
45 Day

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