Last update :
18/04/2024
References   References 3707  
Type : Journal
Web link : http://opp.sagepub.com/content/20/3/183.abstract

Research teams : Mainz - University Medical Center, Johannes Gutenberg
Authors : Spindeldreier K, Thiesen J, Lipp H.P, Krämer I.
Title : Physico-chemical stability of eribulin mesylate containing concentrate and ready-to-administer solutions.
Reference : J Oncol Pharm Practice ; 20: 183-189 2014

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionEribulin mesylate Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0.02 mg/ml 2-8°C Protect from light
28 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0.02 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.205 mg/ml 2-8°C Protect from light
28 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.205 mg/ml 25°C Protect from light
28 Day

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