Last update :
19/11/2024
References   References 3685  
Type : Journal
Web link : http://ejhp.bmj.com/content/24/4/235

Research teams : Leipzig - Hospital Pharmacy, University of Leipzig, Germany
Authors : Pfeifer C, Noll S, Gerecke H, Fassauer G, Jira T, Remane Y , Vogel J, Frontini R, Reinhardt R.
Title : A stability study of amphotericin B, colistin and tobramycin in a hydrophilic suspension commonly used for selective decontamination of the digestive tract by HPLC and in vitro potency measurements.
Reference : EJHP ; 24:4 : 235-241 2017

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
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List of drugs
Oral solutionAmphotericin B Antifungal
Oral solutionColistin sulfate Antibiotic
Oral solutionTobramycin sulfate Antibiotic
Stability of mixtures
plastic bottle methylparaben 9,5 mg
Propylparaben 3 mg
Sodium benzoate 10 mg
Sodium metabisulfite 7,5 mg
Sodium phosphate 132,8 mg
KCl  29,4 mg
Na2HPO4 52, mg
Purified water >> 10 ml
Ampho-Moronal® 5 ml
2-8°C Protect from light
Oral solution Amphotericin B powder ® = ? 500 mg
Oral solution Colistin sulfate powder ® = ? 118 mg
Oral solution Tobramycin sulfate powder ® = ? 121,75 mg
180 Day

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