Last update :
29/10/2024
References   References 3682  
Type : Journal
Web link : http://ejhp.bmj.com/content/23/1/33.abstract

Research teams : Hradec Kralove - Charles University in Prague, Department of Pharmaceutical technology
Authors : Klovrzova S, Zahalka L, Kriz T, Zahalkova O, Matysova L, Sklubalova Z, Horak P.
Title : Extemporaneous sotalol hydrochloride oral solutions for use in paediatric cardiology: formulation and stability study.
Reference : EJHP ;23:33-37 2016

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionSotalol hydrochloride Beta-blocker
Stability in solutions Glass tablets 500 mg
® = ?
Water for injection >> 100 ml
2-8°C Protect from light
180 Day
Stability in solutions Glass tablets 500 mg
® = ?
Citric acid 80 mg
Potassium sorbate 100 mg
Simple syrup 20 g
Water for injection >> 100 ml
2-8°C Protect from light
180 Day
Stability in solutions Glass tablets 500 mg
® = ?
Citric acid 80 mg
Potassium sorbate 100 mg
Sodium saccharin 100 mg
Water for injection >> 100 ml
2-8°C Protect from light
180 Day
Stability in solutions Glass tablets 500 mg
® = ?
Water for injection >> 100 ml
23-27°C Protect from light
180 Day
Stability in solutions Glass tablets 500 mg
® = ?
Citric acid 80 mg
Potassium sorbate 100 mg
Simple syrup 20 g
Water for injection >> 100 ml
23-27°C Protect from light
180 Day
Stability in solutions Glass tablets 500 mg
® = ?
Citric acid 80 mg
Potassium sorbate 100 mg
Sodium saccharin 100 mg
Water for injection >> 100 ml
23-27°C Protect from light
180 Day

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