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References   References 3669  
Type : Journal
Web link : http://www.em-consulte.com/article/949592/article/formulation-and-stability-study-of-a-pediatric-2-p
Research teams : Rennes - University Hospital Pontchaillou, Department of Pharmacy
Authors : Dreno C, Gicquel T, Harry .M, Tribut O, Aubin F, Brandhonneur N, Dollo G.
Title : Formulation and stability study of a pediatric 2% phenylephrine hydrochloride eye drop solution
Reference : Ann Pharm Fr ; 73, 1: 31-36. 2015
Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
List of drugs
Eye-dropsPhenylephrine hydrochloride Sympathomimetic
Stability in solutions Glass powder 200 mg
Sodium phosphate 2 mg
NaCl 0.9% 3,75 ml
Water for injection >> 10 ml
20-25°C Protect from light
60 Day
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