Last update :
19/11/2024
References   References 3534  
Type : Journal
Web link : http://www.ajhp.org/content/70/23/2137.abstract

Research teams : Bordeaux - Laboratoire de Pharmacocinétique et de Pharmacie Clinique
Authors : Legeron R, Xuereb F, Djabarouti S, Saux M.C, Breilh D.
Title : Chemical stability of azacitidine suspensions for injection after cold-chain reconstitution of powder and storage
Reference : Am J Health-Syst Pharm ; 70:2137-2142 2013

Level of Evidence : 
Level of evidence A
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Degradation products identified and quantified

List of drugs
injectionAzacitidine Anticancer drug
Stability in solutions Polypropylen Syringe Water for Injection (4°C) 25 mg/ml 2-8°C Protect from light
48 Hour
conflicting data

  Mentions Légales