Last update :
18/04/2024
References   References 3489  
Type : Journal

Research teams : Barcelona - Hopital Clinic of Barcelona
Authors : Soy D, Roca M, Deulofeu R, Montes E, Codina C, Ribas J.
Title : Estabilidad de las soluciones orales de clohidrato de metadona al 0,1% y 0,5% en suero fisiologico.
Reference : Farm Hosp ; 22, 5: 249-251. 1998

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionMethadone hydrochloride Analgesic
Factors which affect stability Storage Light Induces Degradation
Stability in solutions Plastic bottle Powder 150 mg
Methadone HCl
NaCl 0.9% >> 30 mL
22-28°C Protect from light
180 Day
Stability in solutions Plastic bottle Powder 150 mg
Methadone HCl
NaCl 0.9% >> 30 mL
4°C Protect from light
180 Day
Stability in solutions Syringe Powder 5 mg
Methadone HCl
NaCl 0.9% >> 5 mL
22-28°C Protect from light
180 Day
Stability in solutions Syringe Powder 5 mg
Methadone HCl
NaCl 0.9% >> 5 mL
4°C Protect from light
180 Day

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