Last update :
19/11/2024
References   References 3473  
Type : Journal
Web link : https://doi.org/10.1016/j.ijpharm.2015.10.012
Icone.pdf
1426Ko

Research teams : Marseille - La Timone University Teaching Hospital, Pharmacy Department
Authors : Bennis Y, Savry A, Correard F, Montana M, Sauzet C, Gauthier-Villano L, Pisano P, Pourroy B.
Title : Stability of a highly concentrated solution of epirubicin for conventional transcatheter arterial chemoembolization.
Reference : Int J Pharm ; 495, 2: 956-962. 2015

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Water loss by evaporation 
Comments : 
The method is not specified (poster, letter to the editor)
Degradation products not observed in real conditions

List of drugs
injectionEpirubicin hydrochloride Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 8.33 mg/ml 4°C Protect from light
72 Hour

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