Last update :
29/10/2024
References   References 342  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/42/2/339

Research teams : Corvalis - Oregon State University, College of Pharmacy
Authors : Conklin CA, Kerege JF, Christensen JM.
Title : Stability of an analgesic-sedative combination in glass and plastic single-dose syringes.
Reference : Am J Hosp Pharm ; 42: 339-342. 1985

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Gas chromatography
ultraviolet spectrometry
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionChlorpromazine hydrochloride Anxiolytic
injectionHydroxyzine dihydrochloride Anxiolytic
injectionPethidine hydrochloride Analgesic
Stability of mixtures
Glass Water for Injection 25°C Not specified
injection Chlorpromazine hydrochloride 6,25 mg/ml
injection Hydroxyzine dihydrochloride 12,5 mg/ml
injection Pethidine hydrochloride 25 mg/ml
366 Day
Polyvinyl chloride Water for Injection 4°C Protect from light
injection Chlorpromazine hydrochloride 6,25 mg/ml
injection Hydroxyzine dihydrochloride 12,5 mg/ml
injection Pethidine hydrochloride 25 mg/ml
366 Day

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