Last update :
19/11/2024
References   References 3402  
Type : Journal

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Hecq, J.-D., Lewis, A.L., Vanbeckbergen, D., Athanosopoulos, A., Galanti, L., Jamart, J., Czuczman, P., Chung, T.
Title : Doxorubicin-loaded drug-eluting beads (DC Bead®) for use in transarterial chemoembolization: A stability assessment.
Reference : J Oncol Pharm Practice ; 19, 1: 65-74. 2013

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Comments : 
Degradation products identified and quantified

List of drugs
injectionDoxorubicin hydrochloride Anticancer drug
Stability in solutions Glass DC Beads® 15 mg/ml 2-8°C Protect from light
14 Day

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