Last update :
19/11/2024
References   References 338  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/48/2/280

Research teams : Bethesda - National Institutes of Health Clinical Center
Authors : Lam NP, Kennedy PE, Jarosinski PF, Galleli JF.
Title : Stability of zidovudine in 5% dextrose injection and 0.9% sodium chloride injection.
Reference : Am J Hosp Pharm ; 48: 280-282. 1991

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionZidovudine Antiviral
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 4 mg/ml 25°C Not specified
8 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 4 mg/ml 4°C Protect from light
8 Day

  Mentions Légales