Last update :
19/11/2024
References   References 3347  
Type : Journal
Web link : http://www.ddtjournal.com/getabstract.php?id=509

Research teams : Charleston - Medical University of South Carolina
Authors : Kaushal, G., Sayre, B.E., Prettyman, T.
Title : Stability-indicating HPLC method for the determination of the stability of oxytocin parenteral solutions prepared in polyolefin bags.
Reference : Drug Discov Ther ; 6, 1 : 49-54. 2012

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionOxytocin Various
Stability in solutions Polyolefine Sodium chloride 0,9% 0.02 UI/ml -20°C Protect from light
30 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0.02 UI/ml 2-6°C Protect from light
30 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0.02 UI/ml 22-25°C Light
21 Day

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