Last update :
03/05/2024
References   References 3343  
Type : Poster
Icone.pdf
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Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Vieillard V, da Silva R, Astier A, Paul M.
Title : Physicochemical stability of diluted trastuzumab solutions stored 6 months at 4°C.
Reference : ECOP Congress, Budapest, Hungary 2012

Level of Evidence : 
Level of evidence B+
Physical stability : 
Turbidimetry Protein: Dynamic Light Scattering Protein: Size Exclusion Chromatography 
Chemical stability : 
Protein: Peptide mapping
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Protein: intrared spectrometry and second derivative
Other methods : 
Comments : 
Protein: no biological methods

List of drugs
InjectionTrastuzumab Anticancer drug
Stability in solutions Polypropylene Sodium chloride 0,9% 0,8 mg/ml 4°C Protect from light
180 Day
Stability in solutions Polypropylene Sodium chloride 0,9% 2,4 mg/ml 4°C Protect from light
180 Day

  Mentions Légales