Last update :
03/05/2024
References   References 3341  
Type : Journal

Research teams : Fribourg - University Hospital Freiburg, Department of Pharmacy
Authors : Trittler R, Jung B, Strehl E.
Title : Ist teurer immer auch besser? Analytiklabor der Apotheke unterstütz Einkauf sentcheidungen bei Carboplatin-Präparaten.
Reference : Krankenhauspharmazie ; 7: 331-333. 2001

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products identified
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
InjectionCarboplatin Anticancer drug
Factors which affect stability Solvent Sodium chloride 0,9% Induces Degradation
Stability in solutions Polyvinyl chloride Glucose 5% 0,5 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,5 mg/ml 25°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride Glucose 5% 5 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride Glucose 5% 5 mg/ml 25°C Protect from light
7 Day
Incompatible + Sodium chloride 0,9%

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