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References   References 3337  
Type : Journal
Web link : http://dx.doi.org/10.1136/ejhpharm-2012-000041
Research teams : Bologna - Azienda Ospedaliero-universitaria di Bologna Farmacia Clinica
Authors : Carati D, Masini C, Minguzzi M, Petocchi B, Romanazzi C, Rondoni C, Sangiorgi E, Sferra S, Simonetta S, Stancari A, Locchi F, Z
Title : Stability of bortezomib reconstituted under clinical use conditions in original vials and polypropylene syringes at 4 °C and room temperature.
Reference : EJHP ; 19: 428-431. 2012
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No comments for the degradation products
No visual inspection
List of drugs
InjectionBortezomib Anticancer drug
Stability in solutions Glass Sodium chloride 0,9% 1 mg/ml 2-6°C Protect from light
10 Day
Stability in solutions Glass Sodium chloride 0,9% 1 mg/ml 28°C Protect from light
8 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 2-6°C Protect from light
10 Day
  Mentions Légales