Last update :
28/04/2024
References   References 3331  
Type : Journal
Web link : http://www.em-consulte.com/article/738995/stability-of-the-ready-to-use-solutions-of-eribuli

Research teams : Montpellier - Oncopharmacology Laboratory, Val D'Aurelle Cancer Center
Authors : Poujol S, Dell'ova M, Bekhtari K, Bressolle F, Pinguet F.
Title : Stability of the ready-to-use solutions of eribulin for intravenous infusion.
Reference : Ann Pharm Fr ; 70, 5: 249-255. 2012

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
InjectionEribulin mesylate Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0,015 >> 0,043 mg/ml 18-22°C With or without light
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,015 >> 0,043 mg/ml 2-6°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe None 0,44 mg/ml 18-22°C With or without light
14 Day
Stability in solutions Polypropylen Syringe None 0,44 mg/ml 2-6°C Protect from light
14 Day

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