Last update :
06/05/2024
References   References 333  
Type : Journal
Web link : https://doi.org/10.1177/106002809202600603

Research teams : Chapel Hill - University of North Carolina Hospital, Department of Pharmacy
Authors : Graham CL, Dukes GE, Kao CF, Bertch JM, Hak LJ.
Title : Stability of ondansetron in large-volume parenteral solutions.
Reference : Ann Pharmacotherapy ; 26: 768-771. 1992

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionOndansetron hydrochloride Antiemetic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,024 & 0,096 mg/ml 21-26°C Light
14 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,024 & 0,096 mg/ml 4°C - 6°C Protect from light
14 Day

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