Last update :
19/11/2024
References   References 3293  
Type : Journal
Web link : http://ejhp.bmj.com/content/19/1/52.abstract

Research teams : Kingston upon Thames - Kingston University, Department of Pharmacy
Authors : Patel N, Taki M, Tunstell P, Forsey P, Forbes B.
Title : Stability of dobutamine 500 mg in 50 ml syringes prepared using a Central Intravenous Additive Service
Reference : EJHP ; 19: 52-56. 2012

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionDobutamine hydrochloride Cardiotonic
Factors which affect stability Storage Light Induces Degradation
Stability in solutions Polypropylen Syringe Glucose 5% 10 mg/ml 20°C Protect from light
35 Day
Stability in solutions Polypropylen Syringe Glucose 5% 10 mg/ml 4°C Protect from light
42 Day

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