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References   References 3229  
Type : Journal
Web link : http://www.ajhp.org/content/68/17/1646.abstract
Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Li M, Forest JM, Coursol C, Leclair G.
Title : Stability of cyclosporine solutions stored in polypropylene–polyolefin bags and polypropylene syringes.
Reference : Am J Health-Syst Pharm ;68:1646-1650. 2011
Level of Evidence : 
Level of evidence A+
Physical stability : 
Protein: Dynamic Light Scattering Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
List of drugs
injectionCiclosporin Immunosuppressant
Stability in solutions Polyolefine Sodium chloride 0,9% 0,2 mg/ml 23-27°C Not specified
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 2,5 mg/ml 23-27°C Not specified
14 Day
Stability in solutions Polyolefine Glucose 5% 0,2 mg/ml 23-27°C Not specified
14 Day
Stability in solutions Polyolefine Glucose 5% 2,5 mg/ml 23-27°C Not specified
14 Day
Compatible + Sodium chloride 0,9%
Compatible + Glucose 5%
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