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References   References 3214  
Type : Journal
Web link : http://www.esop.li/ejop.php
Research teams : Fribourg - University Hospital Freiburg, Department of Pharmacy
Authors : Trittler R, Sewell G.
Title : Stability of vincristine (TEVA) in original vials after re-use in dilute infusions in polyolefin bags and in polypropylene syringes.
Reference : EJOP ; 5,1: 10-14. 2011
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products
List of drugs
injectionVincristine sulfate Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0,05 mg/ml 2-8°C Protect from light
84 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,05 mg/ml 25°C Protect from light
84 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,025 mg/ml 2-8°C Protect from light
84 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,025 mg/ml 25°C Protect from light
84 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 2-8°C Protect from light
84 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 25°C Protect from light
84 Day
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