Last update :
29/10/2024
References   References 3198  
Type : Journal
Web link : http://www.sefh.es/sefhpublicaciones/revista.php?id=96&anio=2008

Research teams : Castellón - Hospital General de Castellón, Servicio de Farmacia
Authors : Nebot Martinez J, Alos Alminana M, Diez Sales O.
Title : Estabilidad en suero fisiológico del busulfán intravenoso en un envase de poliolefinas.
Reference : Farm Hosp ; 32, 6 : 344-348. 2008

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
No comments for the degradation products
No visual inspection

List of drugs
injectionBusulfan Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0,12 mg/ml 25°C Not specified
12 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 0,12 mg/ml 4°C Not specified
12 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 0,24 mg/ml 25°C Not specified
8 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 0,24 mg/ml 4°C Not specified
16 Hour

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