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References   References 3172  
Type : Journal
Web link : http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.2010.01160.x/abstract
Research teams : Yunnan - Kunming General Hospital of Chengdu Military Region
Authors : Xu F, Xu G, LSu L, Feng E.
Title : Stability and compatibility of doxofylline with phentolamine mesilate in 0·9% sodium chloride or 5% dextrose injection for intravenous infusion.
Reference : J Clin Pharm Ther ; 36, 1: 99-102. 2011
Level of Evidence : 
Level of evidence A+
Physical stability : 
Particle counting Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionDoxofylline Various
Compatible 0,8 mg/ml + injectionPhentolamine mesylate 0,04 mg/ml + NaCl 0,9% or Glucose 5%
injectionPhentolamine mesylate Vasodilator
Compatible 0,04 mg/ml + injectionDoxofylline 0,8 mg/ml + NaCl 0,9% or Glucose 5%
Stability of mixtures
Polypropylene NaCl 0,9% or Glucose 5% 20-25°C Light
injection Doxofylline 0,74 mg/ml
injection Phentolamine mesylate 0,037 mg/ml
24 Hour
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