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References   References 3087  
Type : Journal
Web link : http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1413-86702008000500011&lng=en&nrm=iso&tlng=en
Research teams : Porto Alegre - Pharmacy School of Federal University of Rio Grande do Sul
Authors : Adams, A.I.H., Morimoto, L.N., Meneghini, L.Z., Bergold, A.M.
Title : Treatment of invasive fungal infections: Stability of voriconazole infusion solutions in PVC bags.
Reference : BJID ; 12, 5: 400-404. 2008
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products not observed in real conditions
List of drugs
InjectionVoriconazole Antifungal
Factors which affect stability Container Polyvinyl chloride Induces Adsorption
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,5 mg/ml 4-7°C Protect from light
11 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,5 mg/ml 4-7°C Protect from light
9 Day
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