| Type : |
Journal |
|
| Research teams : |
Callaghan - School of Pharmacy and Medical Sciences |
| Authors : |
Sharley NA, Yu AMC, Williams DB. |
| Title : |
Stability of mixtures formulated from warfarin tablets or powder. |
| Reference : |
J Pharm Pract and Res ; 37: 95-97. 2007 |
|
| Level of Evidence : |
|
| Physical stability : |
|
| Chemical stability : |
|
| Other methods : |
|
| Comments : |
|
List of drugs
 Warfarin sodium
|
 |
 |
 |
 |
300 mg
Coumadin® |
| Sodium phosphate |
3000 mg |
| tragacanth |
4% 60 ml |
| Sorbitol syrup |
5% 75 ml |
| methylparaben |
240 mg |
| Propylparaben |
60 mg |
| propylene glycol |
3 ml |
| Distilled water |
>> 300 ml |
|
20-24°C |
 |
| 28 |
 |
|
|
|
|
|
300 mg
Marevan® |
| Sodium phosphate |
3000 mg |
| tragacanth |
4% 60 ml |
| Sorbitol syrup |
5% 75 ml |
| methylparaben |
240 mg |
| Propylparaben |
60 mg |
| propylene glycol |
3 ml |
| Distilled water |
>> 300 ml |
|
20-24°C |
|
| 28 |
|
|
|
|
|
Warfarin sodium clathrate
|
|
|
|
 |
324.3 mg
Warfarin sodium clathrate |
| Sodium phosphate |
3000 mg |
| methylparaben |
240 mg |
| Propylparaben |
60 mg |
| propylene glycol |
3 ml |
| Distilled water |
>> 300 ml |
|
20-24°C |
|
| 28 |
|
|
|
|
|
