Last update :
18/04/2024
References   References 2932  
Type : Journal

Research teams : Townsville - James Cook University, School of Pharmacy and molecular Sciences
Authors : Haywood A, Mangan M, Grant G et al.
Title : Extemporaneous isoniazid mixture: stability implications.
Reference : J Pharm Pract and Res ; 35: 181-182. 2005

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionIsoniazid Antibiotic
Factors which affect stability Excipient Sucrose Induces Degradation
Factors which affect stability Excipient Lactose Induces Degradation
Factors which affect stability Excipient Dextrose Induces Degradation
Stability in solutions Not specified Powder 2000 mg
Isoniazid
Citric acid 500 mg
Sodium citrate 2400 mg
Glycerin 80 ml
Hydroxybenzoate solution APF 2 ml
Purified water >> 200 ml
25°C Protect from light
30 Day
Conflicting data
Stability in solutions Not specified Powder 2000 mg
Isoniazid
Citric acid 500 mg
Sodium citrate 2400 mg
Glycerin 80 ml
Hydroxybenzoate solution APF 2 ml
Purified water >> 200 ml
4°C Protect from light
30 Day

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